Angels Notes: No Broken Bone For Torii Hunter, Fernando Rodney Suffers Setback
In other Angels injury news, relief pitcher Fernando Rodney was shut down after suffering a setback in his latest attempt to return from the disabled list, per Mike DGiovanna of the Los Angeles Times . Rodney has been on the DL since June 13 with an upper back strain.
Former Angel Garret Anderson, who retired this offseason and spent 15 years with the Halos, threw out the ceremonial first pitch tonight. He was flanked by his wife and kids, and got a large standing ovation. Much larger than the ovations he got when he returned to Anaheim as an opposing player in 2010 with the Dodgers.
For more Angels news and information, be sure to read the SB Nation blog Halos Heaven .
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Bone Scan Results - News
CHICAGO () - Exelixis Inc's cabozantinib experimental drug shrank bone malignancies from prostate cancer in 76 percent of patients, interim results from a midstage trial show. Of 108 patients so far evaluated by bone scan,
She appealed, filing a functional capacity evaluation (FCE) report with several positive test results. When litigation was threatened, Met Life offered another administrative appeal. The insured submitted a newer FCE, including a bone scan and
Angels outfielder Torii Hunter, who was hit by a pitch from Hiroki Kuroda on Friday night, had a CT scan of his left hand on Saturday. X-rays proved negative, but Hunter was still held out of tonight's lineup against the Dodgers.
The majority of men (78%) had bone metastasis. Among the 65 patients evaluable by bone scan, 56 (86%) experienced complete or partial resolution of bone lesions as early as week 6 of treatment with cabozantinib. In addition, 64% of the 28 men receiving
Another scan was needed to determine if it was just a cyst or a tumor. In October, it was confirmed to be a tumor about the size of a tennis ball. By November, after more scans and two biopsies and one very painful bone marrow biopsy, it was determined
Bone scan “flare” associated with treatment with abiraterone ...
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Ryan et al. — in a small, Phase II clinical trial — used abiraterone acetate to treat 33 men with chemotherapy-naïve, castration-resistant prostate cancer (CRPC).
The patients all received abiraterone acetate 1,000 mg daily with prednisone 5 mg twice daily in continuous 28-day cycles. They were evaluated clinically every month. The goal was to assess bone scan data that did not seem to correspond to PSA and clinical response data.
For the purposes of this study, a bone scan flare was defined as the combination, after 3 months of abiraterone therapy, of a radiology report indicating “disease progression” in the context of a PSA decline of ≥ 50 percent, with bone scan improvement or stability 3 months later.
The results of the study showed the following:
22/33 patients (67 percent) had a PSA decline of ≥ 50 percent at week 12. 26/33 patients (76 percent) had a PSA decline of ≥ 50 percent overall. Undetectable PSA levels (≤ 0.1 ng/ml) were documented in two patients. Average (median) time on therapy was 63 weeks. Average (median) time to PSA progression was 16.3 months. 23/33 patients (70 percent) were evaluable for bone scan flare. 12/23 evaluable patients (52 percent) showed disease progression on bone scan, as indicated in radiologists’ reports. 11/12 patients showing signs of progression subsequently showed improvement or stability. As defined above, bone scan flare was observed in 11/23 evaluable patients (48 percent) or 11/33 enrolled patients (patients). Adverse events to abiraterone therapy were typically grade 1/2 and were consistent with adverse events in prior published reports.Ryan and his colleagues conclude that although clinical responses to abiraterone + prednisone are frequent and durable in men with metastatic CRPC, we need to clarify the impact of bone scan flare on patient management and interpretation of results.
One has to wonder whether short-term use of an antiandrogen like bicalutamide just before and through the time of initiation of abiraterone therapy might help to suppress this bone flare reaction, just as it does with the initiation of LHRH agonist therapy.
BTW : Mum's scan results were NEGATIVE for bone cancer. Big + . Super relieved. She will sleep better tonight. 
Bone scan results not good must have MRI on right tibia. Pictures show an uptake of the radioactive material.
So, this bone scan.... My wrist showed up glowing on one of the bones after the radioactive stuff. Does mean bad things? Results are nxt wed
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